Neural probe system for behavioral neuropharmacology by bi-directional wireless drug delivery and electrophysiology in socially interacting mice

Yousang Yoon; Hyogeun Shin; Donghak Byun; Jiwan Woo; Yakdol Cho; Nakwon Choi; Il-Joo Cho

doi:10.1038/s41467-022-33296-8

Nature Communications (Sep 2022)

Neural probe system for behavioral neuropharmacology by bi-directional wireless drug delivery and electrophysiology in socially interacting mice

Yousang Yoon,
Hyogeun Shin,
Donghak Byun,
Jiwan Woo,
Yakdol Cho,
Nakwon Choi,
Il-Joo Cho

Affiliations

Yousang Yoon: Brain Science Institute, Korea Institute of Science and Technology (KIST)
Hyogeun Shin: Brain Science Institute, Korea Institute of Science and Technology (KIST)
Donghak Byun: Brain Science Institute, Korea Institute of Science and Technology (KIST)
Jiwan Woo: Research Animal Resource Center, Korea Institute of Science and Technology (KIST)
Yakdol Cho: Research Animal Resource Center, Korea Institute of Science and Technology (KIST)
Nakwon Choi: Brain Science Institute, Korea Institute of Science and Technology (KIST)
Il-Joo Cho: Department of Biomedical Sciences, College of Medicine, Korea University

DOI: https://doi.org/10.1038/s41467-022-33296-8
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 19

Abstract

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Technologies for monitoring electrophysiological effects of drugs in behaving animals have limitations. Here the authors report a wireless neural probe system with drug delivery capability for real-time monitoring of drug effects.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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