Synthesis of 2,4,6-Tri-substituted-1,3,5-Triazines

Abstract

Several specific synthetic protocols were developed for the preparation from cyanuric chloride of a range of symmetric and non-symmetric di- and tri-substituted 1,3,5-triazines containing alkyl, aromatic, hindered, chiral and achiral hydroxyalkyl, ester and imidazole groups via sequential nucleophilic substitution of the C-Cl bond by C-O, C-N and C-S bonds.

Keywords

• Cyanuric chloride
• s-triazine
• 1
• 3
• 5-triazine
• melamine derivatives.