Chemical Constituents of Murraya tetramera Huang and Their Repellent Activity against Tribolium castaneum
Chun-Xue You,
Shan-Shan Guo,
Wen-Juan Zhang,
Zhu-Feng Geng,
Jun-Yu Liang,
Ning Lei,
Shu-Shan Du,
Zhi-Wei Deng
Affiliations
Chun-Xue You
Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, No.19, Xinjiekouwai Street, Beijing 100875, China
Shan-Shan Guo
Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, No.19, Xinjiekouwai Street, Beijing 100875, China
Wen-Juan Zhang
Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, No.19, Xinjiekouwai Street, Beijing 100875, China
Zhu-Feng Geng
Analytical and Testing Center, Beijing Normal University, Beijing 100875, China
Jun-Yu Liang
Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, No.19, Xinjiekouwai Street, Beijing 100875, China
Ning Lei
Department of Pharmacy, The General Hospital of the PLA Rocket Force, Xicheng District, Beijing 100088, China
Shu-Shan Du
Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, No.19, Xinjiekouwai Street, Beijing 100875, China
Zhi-Wei Deng
Analytical and Testing Center, Beijing Normal University, Beijing 100875, China
Sixteen compounds were isolated from the leaves and stems of Murraya tetramera Huang. Based on the NMR and MS spectral results, the structures were determined. It was confirmed that the isolated compounds included three new compounds (9, 10 and 13) and one new natural product (8), which were identified asmurratetra A (9), murratetra B (10), murratetra C (13) and [2-(7-methoxy-2-oxochromen-8-yl)-3-methylbut-2-enyl]3-methylbut-2-enoate (8), respectively. Meanwhile, the repellent activity against Tribolium castaneum was investigated for 13 of these isolated compounds. The results showed that the tested compounds had various levels of repellent activity against T. castaneum. Among them, compounds 1 (4(15)-eudesmene-1β,6α-diol), 11 (isoferulic acid) and 16 (2,3-dihydroxypropyl hexadecanoate) showed fair repellent activity against T. castaneum. They might be considered as potential leading compounds for the development of natural repellents.
