Vitae (Jul 2014)

Jaw stiffness and dental extractions due to pharmacodynamic interaction between mirtazapine and chlorpromazine

  • Patricia de Carvalho MASTROIANNI,
  • Fabiana Rossi VARALLO,
  • Manuel MACHUCA

Journal volume & issue
Vol. 21, no. 2

Abstract

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A comprehensive assessment of the patient’s drug related needs allows identifying health problems drug-induced. It has been demonstrated that each dollar spent on clinical pharmacy services reduces the pooled median cost of health by 4.81 dollars. Jaw stiffness (bruxism) can be a serotonergic manifestation related to drugs with serotonin reuptake inhibition activity. Clinical manifestations also include: agitation, tachycardia, high blood pressure, tremor, fever, dyspnea, diarrhea, mental confusion and insomnia.

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