Frontiers in Cardiovascular Medicine (Feb 2024)

Clinical effect of vein of Marshall ethanol infusion on mitral isthmus ablation

  • Wei-Li Ge,
  • Wei-Li Ge,
  • Yi-Fei Lu,
  • Tao Li,
  • Ye Wang,
  • Jie Yin,
  • Xin-Ran Li,
  • Jian-Jun Jiang,
  • Ya-Fei Mi,
  • Tao-Hsin Tung,
  • Tao-Hsin Tung,
  • Su-Hua Yan,
  • Su-Hua Yan

DOI
https://doi.org/10.3389/fcvm.2024.1253554
Journal volume & issue
Vol. 11

Abstract

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PurposeThis study aimed to investigate the effect of Marshall ethanol infusion (VOM-Et) in the vein on mitral isthmus (MI) ablation.MethodsPatients with persistent atrial fibrillation (AF) were grouped into vein of VOM-Et combined with radiofrequency (RF) ablation (VOM-Et-RF) and RF groups. The primary outcome was MI block immediate block rate after surgery. Stratified analysis was also performed for factors affecting the outcome measures.ResultsA total of 118 consecutive patients underwent AF ablation at Taizhou Hospital of Zhejiang Province from January 2018 to December 2021. Successful bidirectional perimitral block was achieved in 96% of patients in VOM-Et-RF (69 of 72) and in 76% of patients in the RF group (35 of 46) (P < 0.01). In the subgroup analysis, male sex, elder than 60 years, Left atrial diameter <55 mm, and AF duration <3 years were associated with the benefits of VOM-Et in AF Patients.ConclusionThe vein of Marshall ethanol infusion for catheter ablation can improve the MI block rate. Male sex, elder age, smaller Left atrial diameter and shorter AF duration may have significant benefits for VOM-Et.

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