International Journal of Molecular Sciences (Mar 2015)

Biomechanical Evaluation of Ti-Nb-Sn Alloy Implants with a Low Young’s Modulus

  • Kenta Takahashi,
  • Naru Shiraishi,
  • Risa Ishiko-Uzuka,
  • Takahisa Anada,
  • Osamu Suzuki,
  • Hiroshi Masumoto,
  • Keiichi Sasaki

DOI
https://doi.org/10.3390/ijms16035779
Journal volume & issue
Vol. 16, no. 3
pp. 5779 – 5788

Abstract

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Dental implants are widely used and are a predictable treatment in various edentulous cases. Occlusal overload may be causally related to implant bone loss and a loss of integration. Stress concentrations may be diminished using a mechanobiologically integrated implant with bone tissue. The purpose of this study was to investigate the biomechanical behavior, biocompatibility and bioactivity of a Ti-Nb-Sn alloy as a dental implant material. It was compared with cpTi. Cell proliferation and alkaline phosphatase (ALP) activity were quantified. To assess the degree of osseointegration, a push-in test was carried out. Cell proliferation and ALP activity in the cells grown on prepared surfaces were similar for the Ti-Nb-Sn alloy and for cpTi in all the experiments. A comparison between the Ti-Nb-Sn alloy implant and the cpTi implant revealed that no significant difference was apparent for the push-in test values. These results suggest that implants fabricated using Ti-Nb-Sn have a similar biological potential as cpTi and are capable of excellent osseointegration.

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