Development of highly efficient platinum catalysts for hydroalkoxylation and hydroamination of unactivated alkenes

Abstract

The direct addition of an O–H (hydroalkoxylation) or an N–H (hydroamination) bond across an alkene is a useful strategy to access biologically relevant heterocycles. Here, the authors report “donor–acceptor”-type platinum catalysts that are effective for both hydroalkoxylation and hydroamination of unactivated alkenes, with broad substrate scope and use of mild conditions.