Journal of Pharmacy and Bioallied Sciences (Jan 2024)

A comparative evaluation of efficacy of root surface biomodification using MTAD, MTAD+I-PRF on adhesion of fibrin clot to dentin sem study

  • Roopali Tapashetti,
  • Neha Bhutani,
  • Shweta Deodurg,
  • Amruta Kulkarni

DOI
https://doi.org/10.4103/jpbs.jpbs_649_23
Journal volume & issue
Vol. 16, no. 5
pp. 431 – 433

Abstract

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Root biomodifiers help in removing the smear layer following mechanical debridement. In this context, we evaluated and compared the in vitro efficacy of MTAD, MTAD+I-PRF, and phosphate-buffered saline-conditioned dentin surfaces by examining the distribution of the fibrin network using scanning electron microscopy. It was concluded that MTAD can serve as a potentially useful root conditioner/biomodifier. Further, the adjunct of MTAD+I-P resulted in more fibrin network linkage on the dentinal surface when compared to MTAD alone which can be of great utility in Advanced Regenerative Therapy.

Keywords