SHAPE-guided RNA structure homology search and motif discovery

Edoardo Morandi; Martijn J. van Hemert; Danny Incarnato

doi:10.1038/s41467-022-29398-y

Nature Communications (Mar 2022)

SHAPE-guided RNA structure homology search and motif discovery

Edoardo Morandi,
Martijn J. van Hemert,
Danny Incarnato

Affiliations

Edoardo Morandi: Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen
Martijn J. van Hemert: Department of Medical Microbiology, Molecular Virology Laboratory, Leiden University Medical Center
Danny Incarnato: Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen

DOI: https://doi.org/10.1038/s41467-022-29398-y
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 7

Abstract

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SHAPEwarp is a method that allows identifying structurally-similar RNAs by direct comparison of reactivity profiles derived from chemical probing experiments. Its application to viral genomes identified conserved RNA structure elements.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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