PLoS ONE (Jan 2019)

Management of patients with acute ST-elevation myocardial infarction: Results of the FAST-MI Tunisia Registry.

  • Faouzi Addad,
  • Abdallah Mahdhaoui,
  • Jeridi Gouider,
  • Essia Boughzela,
  • Samir Kamoun,
  • Mohamed Rachid Boujnah,
  • Habib Haouala,
  • Habib Gamra,
  • Faouzi Maatouk,
  • Ali Ben Khalfallah,
  • Salem Kachboura,
  • Hedi Baccar,
  • Nejeh Ben Halima,
  • Ali Guesmi,
  • Khaled Sayahi,
  • Wissem Sdiri,
  • Ali Neji,
  • Ahmed Bouakez,
  • Sami Milouchi,
  • Kais Battikh,
  • Yves Jullieres,
  • Nicolas Danchin,
  • Jean Jacques Monsuez,
  • Genevieve Mulak,
  • Albert Hagege,
  • Vincent Bataille,
  • Rafik Chettaoui,
  • Mohamed Sami Mourali,
  • FAST-MI Tunisia investigators

DOI
https://doi.org/10.1371/journal.pone.0207979
Journal volume & issue
Vol. 14, no. 2
p. e0207979

Abstract

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BackgroundThe FAST-MI Tunisia registry was set up by the Tunisian Society of Cardiology and Cardiovascular Surgery to assess the demographic and clinical characteristics, management and hospital outcome of patients with ST-elevation myocardial infarction (STEMI).MethodsData for 459 consecutive patients (mean age 60.8 years; 88.5% male) with STEMI, treated in 16 public hospitals (representing 72.2% of public hospitals in Tunisia treating STEMI patients), were collected prospectively.The most common risk factors were smoking (63.6%), hypertension (39.7%), diabetes (32%) and dyslipidaemia (18.2%).ResultsAmong the 459 patients, 61.8% received reperfusion therapy: 30% with primary percutaneous coronary intervention (PPCI) and 31.8% with intravenous fibrinolysis (IF) (28.6% with pre-hospital thrombolysis). The median time from symptom onset to thrombolysis was 185 min and to PPCI was 358 min. In-hospital mortality was 5.3%. Compared with those managed at regional hospitals, patients managed at interventional university hospitals (n = 357) were more likely to receive reperfusion therapy (52.9% vs. 34.1%; pConclusionsData from the FAST-MI Tunisia registry show that a pharmaco-invasive strategy of management for STEMI should be promoted in non-interventional regional hospitals.