Nature Communications (Oct 2018)

Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development

  • Jinhua Liu,
  • Yapu Li,
  • Jingyuan Tong,
  • Jie Gao,
  • Qing Guo,
  • Lingling Zhang,
  • Bingrui Wang,
  • Hui Zhao,
  • Hongtao Wang,
  • Erlie Jiang,
  • Ryo Kurita,
  • Yukio Nakamura,
  • Osamu Tanabe,
  • James Douglas Engel,
  • Emery H. Bresnick,
  • Jiaxi Zhou,
  • Lihong Shi

DOI
https://doi.org/10.1038/s41467-018-06883-x
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 15

Abstract

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LncRNAs modulate diverse physiological cellular processes, however, their involvement in heme-dependent processes are not yet clear. Here the authors reveal the role of lncRNA UCA1 in erythroid cell development.