Hydrogen medicine: A rising star in gas medicine

Dongyue Du; Lin Zhao; Meihua Shen; Mami Noda; Shucun Qin; Jiangang Long; Xuejun Sun; Jiankang Liu

doi:10.1142/S2575900020300052

Traditional Medicine and Modern Medicine (Sep 2020)

Affiliations

Dongyue Du: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, P. R. China
Lin Zhao: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, P. R. China
Meihua Shen: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, P. R. China
Mami Noda: Laboratory of Pathophysiology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan
Shucun Qin: Taishan Institute for Hydrogen Biomedicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai’an 271000, P. R. China
Jiangang Long: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, P. R. China
Xuejun Sun: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, P. R. China
Jiankang Liu: Center for Mitochondrial Biology and Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, P. R. China

DOI: https://doi.org/10.1142/S2575900020300052
Journal volume & issue: Vol. 3, no. 3
pp. 153 – 161

Abstract

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Gas medicine, including O2, NO, H2S, CO, CH4, has played important roles in prevention and treatment of diseases for a long time. Molecular hydrogen (H2), the smallest diatomic molecule in nature, has become a rising star in gas medicine in the past decades. Many studies have shown that H2 has preventive and therapeutic effects on various diseases through its selective antioxidant activity. H2, as a non-toxic gas for the human body and convenience to obtain, has provided a great possibility to be used widely. Currently, the main difficulties in hydrogen medicine are lack of definitive clinical evidence and the molecular basis of hydrogen effects. In this paper, the authors have conducted a comprehensive review and analysis of these issues, and also proposed the possibility of developing Hydrogen Biology and Hydrogen Medicine as new disciplines of biology and medicine.

Published in Traditional Medicine and Modern Medicine

ISSN: 2575-9000 (Print); 2575-9019 (Online)
Publisher: World Scientific Publishing
Country of publisher: Singapore
LCC subjects: Medicine: Other systems of medicine
Website: https://www.worldscientific.com/worldscinet/tmmm

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