Communications Biology (Oct 2021)

The application of tissue-engineered fish swim bladder vascular graft

  • Hualong Bai,
  • Peng Sun,
  • Haoliang Wu,
  • Shunbo Wei,
  • Boao Xie,
  • Wang Wang,
  • Yachen Hou,
  • Jing’an Li,
  • Alan Dardik,
  • Zhuo Li

DOI
https://doi.org/10.1038/s42003-021-02696-9
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 11

Abstract

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Bai et al. employ a fish bladder-derived decellularized matrix for the engineering of vascular grafts. The authors show that rapamycin-coated bladder-derived vascular grafts can be implanted as an interposition graft in rats, and that these vascular grafts showed decreased neointimal thickness both in artery and veins.