Case Fatality Rate among Septicemia Patients in a Tertiary Care Hospital of Western India

Abstract

Objective: The present study was carried out to study common sites of infection and organisms leading to sepsis commonly, to study various agents and host factors leading to sepsis and their prognostic importance and fatality rate due to sepsis. Method: The present prospective study was conducted in patients with clinical features suggestive of sepsis were included in the study. Gram stain and culture of the material from the primary site of infection for the microbial etiology was taken. Other appropriate laboratory data depending upon the requirement was done. Results: Among 50 cases of sepsis studied, 34 were male (68%) and 16 were female (32%). DM was the common co-morbid condition along with IHD, COPD, pulmonary Koch’s, hypertension and alcoholic liver disease. The common complications were respiratory failure, kidney failure and shock. The overall case fatality rate was found to be 42%.It was observed that mortality was higher among the patients presenting with shock (73%) and abnormal liver function tests (70%). Conclusion: Higher fatality rate was associated with age above 58 years, female gender, increase in co-morbid conditions, patients presenting with shock and abnormal liver function tests and increase in number of organ failures. Mortality was higher in patients with positive blood culture and patients with gram negative septicemia.

Keywords

• Sepsis
• fataity rate
• Gram stain
• Septicemia
• Gram positive
• Gram negative