Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)

Elie Haddad; Manfred Hoenig

doi:10.3389/fped.2019.00481

Frontiers in Pediatrics (Nov 2019)

Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)

Elie Haddad,
Manfred Hoenig

Affiliations

Elie Haddad: CHU Sainte-Justine, Department of Pediatrics, Microbiology, Immunology and Infectious Diseases, University of Montreal, Montreal, QC, Canada
Manfred Hoenig: Department of Pediatrics, University Medical Center Ulm, Ulm, Germany

DOI: https://doi.org/10.3389/fped.2019.00481
Journal volume & issue: Vol. 7

Abstract

Read online

Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell transplantation. Therapeutic strategies may differ between subtypes and the inherent reduced capacity or inablility to reject a graft have to be considered.

Published in Frontiers in Pediatrics

ISSN: 2296-2360 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Pediatrics
Website: http://journal.frontiersin.org/journal/pediatrics

About the journal

Abstract

Keywords