P1492: PHARMACODYNAMIC EFFECTS OF AG-946, A HIGHLY POTENT NOVEL ACTIVATOR OF PYRUVATE KINASE, IN EX VIVO TREATMENT OF RED BLOOD CELLS FROM SICKLE CELL DISEASE PATIENTS
M. Rab,
M. van Dijk,
J. Bos,
B. van Oirschot,
J. Gerrits,
P. Kosinski,
C. Kung,
J. Jans,
E. van Beers,
L. Dang,
R. van Wijk
Affiliations
M. Rab
1 Central Diagnostic Laboratory Research
M. van Dijk
1 Central Diagnostic Laboratory Research
J. Bos
1 Central Diagnostic Laboratory Research
B. van Oirschot
1 Central Diagnostic Laboratory Research
J. Gerrits
2 Metabolic Diagnostics, University Medical Center Utrecht, Utrecht, Netherlands
P. Kosinski
3 Agios Pharmaceuticals inc., Cambridge, United States of America
C. Kung
4 Agios Pharmaceuticals inc., Cambridge
J. Jans
2 Metabolic Diagnostics, University Medical Center Utrecht, Utrecht, Netherlands
E. van Beers
5 Van Creveldkliniek, University Medical Center Utrecht, Utrecht, Netherlands
L. Dang
3 Agios Pharmaceuticals inc., Cambridge, United States of America
