Nature Communications (Apr 2018)

μ-opioid receptor system mediates reward processing in humans

  • Lauri Nummenmaa,
  • Tiina Saanijoki,
  • Lauri Tuominen,
  • Jussi Hirvonen,
  • Jetro J. Tuulari,
  • Pirjo Nuutila,
  • Kari Kalliokoski

DOI
https://doi.org/10.1038/s41467-018-03848-y
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 7

Abstract

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μ-opioid signalling has a known role in the response to various rewarding stimuli, including pleasant foods. Here, Nummenmaa et al. show using PET and fMRI that individual differences in brain μ-opioid receptor density predict the strength of the neural response to highly palatable foods in humans