Revista de la Facultad de Ciencias de la Salud (Mar 2011)

Familial hyperlipidemia: Resolving a case using evidence-based medicine

  • Edison Benavides-Hernández,
  • Alexander Burbano-Imbachí,
  • Hernando Almonacid-Córdoba,
  • Cristina Collazos-Cerón,
  • Victor Castro-Cruz,
  • Álvaro Bastidas-Velasco,
  • Andrea salas-Mesías,
  • Jaime Bonilla-Medina,
  • Álvaro Narváez-Gómez,
  • Mario Delgado-Noguera

Journal volume & issue
Vol. 13, no. 1
pp. 20 – 26

Abstract

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Background: familial hypercholesterolemia (FH) and familial hyperlipidemia combined (HFC) are metabolic disorders of lipids associated with increase of the risk for cerebrovascular disease. Clinical case: 8-years-old Indigenous child with HFC presented right hemiparesis, motor aphasia and right central facial paralysis for a cerebral ischemic accident; in addition, he had altered lipid profile and family history of hypercholesterolemia. Methodology: this article used patient`s therapeutic approach using evidence-based medicine (EBM), started from a structured clinical question and PubMED search. Four systematic reviews were included. Discussion: statins are safe in children with HF and HFC are effective in improving lipid profile. EBM methodology could help to solve similar therapeutic problems.

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