Analisis Antibodi IgG Spesifik Fimbria Porphyromonas gingivalis dengan Metoda Elisa pada Penderita Early-Onset Periodontitis

Abstract

The adherence of bacteria to the host tissues is a first step in the development of infections. Bacterial fimbriae have been shown to play an important role in the interaction between bacteria and host cells or among bacterial cells. Optical density of serum IgG specific Porphyromonas gingivalis strain ATCC 33277 fimbriae antibodies has been estimated in 32 cases of Early-Onset Periodontitis and 14 healthy periodontal subjects as control. The mean level of IgG were significantly elevated (p=0,000) in their cases. The data support the role of P. gingivalis as a key pathogen in Early-Onset Periodontitis.