Nature Communications (Sep 2017)

Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb

  • Daniel T. Case,
  • Shawn D. Burton,
  • Jeremy Y. Gedeon,
  • Sean-Paul G. Williams,
  • Nathaniel N. Urban,
  • Rebecca P. Seal

DOI
https://doi.org/10.1038/s41467-017-00765-4
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 9

Abstract

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Cholinergic neurons innervate multiple layers in the main olfactory bulb but the precise circuitry of this input is not known. Here the authors show that VGLUT3+ cholinergic neurons selectively innervate deep short axon cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic postsynaptic currents.