Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis

Abstract

Interleukin-25 has been reported to have anticancer activity with very little effect on non-malignant cells. Here, the authors show that a synthetic phytochemical can be used to induce the secretion of Interleukin-25 from tumour associated fibroblasts resulting in impaired tumour metastasis.