Galicia Clínica (Dec 2018)

Oligodendroglioma anaplásico metastático

  • Ana Sofia Patrão,
  • Inês Sequeira,
  • Manuel Jacóme,
  • Joaquina Maurício

DOI
https://doi.org/10.22546/50/1598
Journal volume & issue
Vol. 79, no. 4
pp. 127 – 129

Abstract

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Metastization from a brain primary tumor is a rare event. The mechanisms of metastization and the best treatment approach are still unknown. Knowledge is, so far, mostly based on case reports. We report a case of a patient with the diagnosis of an anaplastic oligodendroglioma, presenting, 9 months after the brain surgery, with spinal cord compression and pleural effusion. The patient underwent surgery for decompression and local radiotherapy to D12-L5, 30 Gy, 10 fractions and the histology confirmed metastasis of oligodendroglioma. Citology of pleural liquid confirmed the same origin. The patient started temozolomide with good clinical response and stabilization of the disease for 9 months. This is an uncommon case of bone and pleural metastization of anaplastic oligodendroglioma that had a good response to temozolomide in the metastatic setting.

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