Journal of Investigative Medicine High Impact Case Reports (Oct 2017)

Autoimmune Pancreatitis Type 2: Case Report

  • Chidinma Onweni MD,
  • Harika Balagoni MD,
  • Jennifer M. Treece MD, MBA,
  • Emmanuel Addo Yobo MD,
  • Archi Patel MD,
  • Jennifer Phemister MD,
  • Manoj Srinath MD,
  • Mark F. Young MD

DOI
https://doi.org/10.1177/2324709617734245
Journal volume & issue
Vol. 5

Abstract

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A middle-aged man presents with acute pancreatitis of unknown etiology and is found to have a presentation consistent with the diagnosis of type 2 autoimmune pancreatitis (AIP). AIP is a group of rare heterogeneous diseases that are challenging to diagnose. There are 2 types of AIP. Type 1 disease is the more common worldwide than type 2 AIP. While type 1 AIP is associated with IgG4-positive antibodies, type 2 AIP is IgG4 antibody negative. Both types of AIP are responsive to corticosteroid treatment. Although type 1 AIP has more extrapancreatic manifestations and more commonly relapses, this is a case of a patient with type 2 AIP with inflammatory bowel disease and relapsing course.