Genome-scale metabolic reconstructions of multiple Salmonella strains reveal serovar-specific metabolic traits

Yara Seif; Erol Kavvas; Jean-Christophe Lachance; James T. Yurkovich; Sean-Paul Nuccio; Xin Fang; Edward Catoiu; Manuela Raffatellu; Bernhard O. Palsson; Jonathan M. Monk

doi:10.1038/s41467-018-06112-5

Nature Communications (Sep 2018)

Genome-scale metabolic reconstructions of multiple Salmonella strains reveal serovar-specific metabolic traits

Yara Seif,
Erol Kavvas,
Jean-Christophe Lachance,
James T. Yurkovich,
Sean-Paul Nuccio,
Xin Fang,
Edward Catoiu,
Manuela Raffatellu,
Bernhard O. Palsson,
Jonathan M. Monk

Affiliations

Yara Seif: Department of Bioengineering, University of California
Erol Kavvas: Department of Bioengineering, University of California
Jean-Christophe Lachance: Département de Biologie, Université de Sherbrooke
James T. Yurkovich: Department of Bioengineering, University of California
Sean-Paul Nuccio: Department of Pediatrics, University of California
Xin Fang: Department of Bioengineering, University of California
Edward Catoiu: Department of Bioengineering, University of California
Manuela Raffatellu: Department of Pediatrics, University of California
Bernhard O. Palsson: Department of Bioengineering, University of California
Jonathan M. Monk: Department of Bioengineering, University of California

DOI: https://doi.org/10.1038/s41467-018-06112-5
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 12

Abstract

Read online

Salmonella serovars colonize a wide range of hosts but the underlying genetic determinants remain poorly understood. Here, Seif et al. use a network-based computational analysis to link specific metabolic capabilities with host range and nutritional niche.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal