mSystems (Jun 2021)

The Salivary Microbiota, Cytokines, and Metabolome in Patients with Ankylosing Spondylitis Are Altered and More Proinflammatory than Those in Healthy Controls

  • Longxian Lv,
  • Huiyong Jiang,
  • Ren Yan,
  • Danyi Xu,
  • Kaicen Wang,
  • Qiangqiang Wang,
  • Xiaoxiao Chen,
  • Lanjuan Li

DOI
https://doi.org/10.1128/mSystems.01173-20
Journal volume & issue
Vol. 6, no. 3

Abstract

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Ankylosing spondylitis (AS) affects as much as 0.32% of the population in some districts and causes work disability in one-third of these patients. Microbes are considered to play important roles in AS pathogenesis, and the mouth links the environment to the lungs and the gut.