Multi-locus sequence analysis reveals a novel sequence type of Chlamydia trachomatis in Saratov Region, Russia

Abstract

Chlamydia trachomatis is the causative agent of a variety of chlamydial infections in humans with a predominantly (up to 80%) asymptomatic course of disease. In this study, a potentially novel C. trachomatis sequence type (ST) was detected in an asymptomatic man who has sex with a man among the nine STs revealed in urogenital swabs from individuals with chlamydia (n = 18). Phylogenetically this ST270 clustered separately as a single clade to an ST13-founded group of C. trachomatis strains and differed from the latter by a single allele, hflX. This finding emphasizes the importance of careful investigation of individuals with asymptomatic chlamydia infections. Keywords: Chlamydia trachomatis, men-who-have-sex-with-men, multilocus sequence typing, ompA, sequence type