Fatigue behavior and osseointegration of porous Ti-6Al-4V scaffolds with dense core for dental application

Yinze Xiong; Wei Wang; Ruining Gao; Hang Zhang; Lanlan Dong; Jiawei Qin; Bibo Wang; Weitao Jia; Xiang Li

Materials & Design (Oct 2020)

Fatigue behavior and osseointegration of porous Ti-6Al-4V scaffolds with dense core for dental application

Yinze Xiong,
Wei Wang,
Ruining Gao,
Hang Zhang,
Lanlan Dong,
Jiawei Qin,
Bibo Wang,
Weitao Jia,
Xiang Li

Affiliations

Yinze Xiong: School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai, 200240, China
Wei Wang: Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China
Ruining Gao: School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai, 200240, China
Hang Zhang: School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai, 200240, China
Lanlan Dong: School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai, 200240, China
Jiawei Qin: School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai, 200240, China
Bibo Wang: Orthopaedic Department, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China
Weitao Jia: Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China; Correspondence to: Weitao Jia, Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China
Xiang Li: School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai, 200240, China; Correspondence to: Xiang Li, School of Mechanical Engineering, Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration, Shanghai, 200240, China

Journal volume & issue: Vol. 195
p. 108994

Abstract

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Increasing research has supported the utilization of a porous Ti-6Al-4V (T64) scaffold for dental applications because of its low stiffness and well-constructed pore structure that allows for bone ingrowth. Selective laser melting (SLM) has enabled the fabrication of T64 lattice structures, but most studies indicate limited fatigue performance. In this study, porous scaffolds with dense cores of varying diameter were designed in order to test their effectiveness in enhancing the strength of the scaffold. The static mechanical properties and fatigue performance of the resulting SLM-printed T64 porous structures were systematically examined. The mechanisms of this design were analyzed using finite element (FE) simulation, and osseointegration responses were investigated by in vitro and in vivo tests. Our design was found to effectively balance the biological requirements (low stiffness and high porosity) and mechanical demands (high yield strength and high fatigue strength) of the SLM-fabricated T64 lattice structure, and shows good potential for application in dental implants.

Published in Materials & Design

ISSN: 0264-1275 (Print); 1873-4197 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials
Website: https://www.journals.elsevier.com/materials-and-design

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