Metabolomics and Integrative Omics for the Development of Thai Traditional Medicine

Sakda Khoomrung; Sakda Khoomrung; Sakda Khoomrung; Kwanjeera Wanichthanarak; Kwanjeera Wanichthanarak; Intawat Nookaew; Intawat Nookaew; Intawat Nookaew; Onusa Thamsermsang; Patcharamon Seubnooch; Tawee Laohapand; Pravit Akarasereenont; Pravit Akarasereenont; Pravit Akarasereenont

doi:10.3389/fphar.2017.00474

Frontiers in Pharmacology (Jul 2017)

Metabolomics and Integrative Omics for the Development of Thai Traditional Medicine

Sakda Khoomrung,
Sakda Khoomrung,
Sakda Khoomrung,
Kwanjeera Wanichthanarak,
Kwanjeera Wanichthanarak,
Intawat Nookaew,
Intawat Nookaew,
Intawat Nookaew,
Onusa Thamsermsang,
Patcharamon Seubnooch,
Tawee Laohapand,
Pravit Akarasereenont,
Pravit Akarasereenont,
Pravit Akarasereenont

Affiliations

Sakda Khoomrung: Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Sakda Khoomrung: Siriraj Metabolomics and Phenomics Center, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Sakda Khoomrung: Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of TechnologyGothenburg, Sweden
Kwanjeera Wanichthanarak: Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Kwanjeera Wanichthanarak: Siriraj Metabolomics and Phenomics Center, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Intawat Nookaew: Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Intawat Nookaew: Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of TechnologyGothenburg, Sweden
Intawat Nookaew: Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical SciencesLittle Rock, AR, United States
Onusa Thamsermsang: Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Patcharamon Seubnooch: Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Tawee Laohapand: Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Pravit Akarasereenont: Center of Applied Thai Traditional Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Pravit Akarasereenont: Siriraj Metabolomics and Phenomics Center, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand
Pravit Akarasereenont: Department of Pharmacology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand

DOI: https://doi.org/10.3389/fphar.2017.00474
Journal volume & issue: Vol. 8

Abstract

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In recent years, interest in studies of traditional medicine in Asian and African countries has gradually increased due to its potential to complement modern medicine. In this review, we provide an overview of Thai traditional medicine (TTM) current development, and ongoing research activities of TTM related to metabolomics. This review will also focus on three important elements of systems biology analysis of TTM including analytical techniques, statistical approaches and bioinformatics tools for handling and analyzing untargeted metabolomics data. The main objective of this data analysis is to gain a comprehensive understanding of the system wide effects that TTM has on individuals. Furthermore, potential applications of metabolomics and systems medicine in TTM will also be discussed.

Published in Frontiers in Pharmacology

ISSN: 1663-9812 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://journal.frontiersin.org/journals/pharmacology

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