Nature Communications (Jan 2019)
Shared heritability and functional enrichment across six solid cancers
- Xia Jiang,
- Hilary K. Finucane,
- Fredrick R. Schumacher,
- Stephanie L. Schmit,
- Jonathan P. Tyrer,
- Younghun Han,
- Kyriaki Michailidou,
- Corina Lesseur,
- Karoline B. Kuchenbaecker,
- Joe Dennis,
- David V. Conti,
- Graham Casey,
- Mia M. Gaudet,
- Jeroen R. Huyghe,
- Demetrius Albanes,
- Melinda C. Aldrich,
- Angeline S. Andrew,
- Irene L. Andrulis,
- Hoda Anton-Culver,
- Antonis C. Antoniou,
- Natalia N. Antonenkova,
- Susanne M. Arnold,
- Kristan J. Aronson,
- Banu K. Arun,
- Elisa V. Bandera,
- Rosa B. Barkardottir,
- Daniel R. Barnes,
- Jyotsna Batra,
- Matthias W. Beckmann,
- Javier Benitez,
- Sara Benlloch,
- Andrew Berchuck,
- Sonja I. Berndt,
- Heike Bickeböller,
- Stephanie A. Bien,
- Carl Blomqvist,
- Stefania Boccia,
- Natalia V. Bogdanova,
- Stig E. Bojesen,
- Manjeet K. Bolla,
- Hiltrud Brauch,
- Hermann Brenner,
- James D. Brenton,
- Mark N. Brook,
- Joan Brunet,
- Hans Brunnström,
- Daniel D. Buchanan,
- Barbara Burwinkel,
- Ralf Butzow,
- Gabriella Cadoni,
- Trinidad Caldés,
- Maria A. Caligo,
- Ian Campbell,
- Peter T. Campbell,
- Géraldine Cancel-Tassin,
- Lisa Cannon-Albright,
- Daniele Campa,
- Neil Caporaso,
- André L. Carvalho,
- Andrew T. Chan,
- Jenny Chang-Claude,
- Stephen J. Chanock,
- Chu Chen,
- David C. Christiani,
- Kathleen B. M. Claes,
- Frank Claessens,
- Judith Clements,
- J. Margriet Collée,
- Marcia Cruz Correa,
- Fergus J. Couch,
- Angela Cox,
- Julie M. Cunningham,
- Cezary Cybulski,
- Kamila Czene,
- Mary B. Daly,
- Anna deFazio,
- Peter Devilee,
- Orland Diez,
- Manuela Gago-Dominguez,
- Jenny L. Donovan,
- Thilo Dörk,
- Eric J. Duell,
- Alison M. Dunning,
- Miriam Dwek,
- Diana M. Eccles,
- Christopher K. Edlund,
- Digna R Velez Edwards,
- Carolina Ellberg,
- D. Gareth Evans,
- Peter A. Fasching,
- Robert L. Ferris,
- Triantafillos Liloglou,
- Jane C. Figueiredo,
- Olivia Fletcher,
- Renée T. Fortner,
- Florentia Fostira,
- Silvia Franceschi,
- Eitan Friedman,
- Steven J. Gallinger,
- Patricia A. Ganz,
- Judy Garber,
- José A. García-Sáenz,
- Simon A. Gayther,
- Graham G. Giles,
- Andrew K. Godwin,
- Mark S. Goldberg,
- David E. Goldgar,
- Ellen L. Goode,
- Marc T. Goodman,
- Gary Goodman,
- Kjell Grankvist,
- Mark H. Greene,
- Henrik Gronberg,
- Jacek Gronwald,
- Pascal Guénel,
- Niclas Håkansson,
- Per Hall,
- Ute Hamann,
- Freddie C. Hamdy,
- Robert J. Hamilton,
- Jochen Hampe,
- Aage Haugen,
- Florian Heitz,
- Rolando Herrero,
- Peter Hillemanns,
- Michael Hoffmeister,
- Estrid Høgdall,
- Yun-Chul Hong,
- John L. Hopper,
- Richard Houlston,
- Peter J. Hulick,
- David J. Hunter,
- David G. Huntsman,
- Gregory Idos,
- Evgeny N. Imyanitov,
- Sue Ann Ingles,
- Claudine Isaacs,
- Anna Jakubowska,
- Paul James,
- Mark A. Jenkins,
- Mattias Johansson,
- Mikael Johansson,
- Esther M. John,
- Amit D. Joshi,
- Radka Kaneva,
- Beth Y. Karlan,
- Linda E. Kelemen,
- Tabea Kühl,
- Kay-Tee Khaw,
- Elza Khusnutdinova,
- Adam S. Kibel,
- Lambertus A. Kiemeney,
- Jeri Kim,
- Susanne K. Kjaer,
- Julia A. Knight,
- Manolis Kogevinas,
- Zsofia Kote-Jarai,
- Stella Koutros,
- Vessela N. Kristensen,
- Jolanta Kupryjanczyk,
- Martin Lacko,
- Stephan Lam,
- Diether Lambrechts,
- Maria Teresa Landi,
- Philip Lazarus,
- Nhu D. Le,
- Eunjung Lee,
- Flavio Lejbkowicz,
- Heinz-Josef Lenz,
- Goska Leslie,
- Davor Lessel,
- Jenny Lester,
- Douglas A. Levine,
- Li Li,
- Christopher I. Li,
- Annika Lindblom,
- Noralane M. Lindor,
- Geoffrey Liu,
- Fotios Loupakis,
- Jan Lubiński,
- Lovise Maehle,
- Christiane Maier,
- Arto Mannermaa,
- Loic Le Marchand,
- Sara Margolin,
- Taymaa May,
- Lesley McGuffog,
- Alfons Meindl,
- Pooja Middha,
- Austin Miller,
- Roger L. Milne,
- Robert J. MacInnis,
- Francesmary Modugno,
- Marco Montagna,
- Victor Moreno,
- Kirsten B. Moysich,
- Lorelei Mucci,
- Kenneth Muir,
- Anna Marie Mulligan,
- Katherine L. Nathanson,
- David E. Neal,
- Andrew R. Ness,
- Susan L. Neuhausen,
- Heli Nevanlinna,
- Polly A. Newcomb,
- Lisa F. Newcomb,
- Finn Cilius Nielsen,
- Liene Nikitina-Zake,
- Børge G. Nordestgaard,
- Robert L. Nussbaum,
- Kenneth Offit,
- Edith Olah,
- Ali Amin Al Olama,
- Olufunmilayo I. Olopade,
- Andrew F. Olshan,
- Håkan Olsson,
- Ana Osorio,
- Hardev Pandha,
- Jong Y. Park,
- Nora Pashayan,
- Michael T. Parsons,
- Tanja Pejovic,
- Kathryn L. Penney,
- Wilbert H M. Peters,
- Catherine M. Phelan,
- Amanda I. Phipps,
- Dijana Plaseska-Karanfilska,
- Miranda Pring,
- Darya Prokofyeva,
- Paolo Radice,
- Kari Stefansson,
- Susan J. Ramus,
- Leon Raskin,
- Gad Rennert,
- Hedy S. Rennert,
- Elizabeth J. van Rensburg,
- Marjorie J. Riggan,
- Harvey A. Risch,
- Angela Risch,
- Monique J. Roobol,
- Barry S. Rosenstein,
- Mary Anne Rossing,
- Kim De Ruyck,
- Emmanouil Saloustros,
- Dale P. Sandler,
- Elinor J. Sawyer,
- Matthew B. Schabath,
- Johanna Schleutker,
- Marjanka K. Schmidt,
- V. Wendy Setiawan,
- Hongbing Shen,
- Erin M. Siegel,
- Weiva Sieh,
- Christian F. Singer,
- Martha L. Slattery,
- Karina Dalsgaard Sorensen,
- Melissa C. Southey,
- Amanda B. Spurdle,
- Janet L. Stanford,
- Victoria L. Stevens,
- Sebastian Stintzing,
- Jennifer Stone,
- Karin Sundfeldt,
- Rebecca Sutphen,
- Anthony J. Swerdlow,
- Eloiza H. Tajara,
- Catherine M. Tangen,
- Adonina Tardon,
- Jack A. Taylor,
- M. Dawn Teare,
- Manuel R. Teixeira,
- Mary Beth Terry,
- Kathryn L. Terry,
- Stephen N. Thibodeau,
- Mads Thomassen,
- Line Bjørge,
- Marc Tischkowitz,
- Amanda E. Toland,
- Diana Torres,
- Paul A. Townsend,
- Ruth C. Travis,
- Nadine Tung,
- Shelley S. Tworoger,
- Cornelia M. Ulrich,
- Nawaid Usmani,
- Celine M. Vachon,
- Els Van Nieuwenhuysen,
- Ana Vega,
- Miguel Elías Aguado-Barrera,
- Qin Wang,
- Penelope M. Webb,
- Clarice R. Weinberg,
- Stephanie Weinstein,
- Mark C. Weissler,
- Jeffrey N. Weitzel,
- Catharine M. L. West,
- Emily White,
- Alice S. Whittemore,
- H-Erich Wichmann,
- Fredrik Wiklund,
- Robert Winqvist,
- Alicja Wolk,
- Penella Woll,
- Michael Woods,
- Anna H. Wu,
- Xifeng Wu,
- Drakoulis Yannoukakos,
- Wei Zheng,
- Shanbeh Zienolddiny,
- Argyrios Ziogas,
- Kristin K. Zorn,
- Jacqueline M. Lane,
- Richa Saxena,
- Duncan Thomas,
- Rayjean J. Hung,
- Brenda Diergaarde,
- James McKay,
- Ulrike Peters,
- Li Hsu,
- Montserrat García-Closas,
- Rosalind A. Eeles,
- Georgia Chenevix-Trench,
- Paul J. Brennan,
- Christopher A. Haiman,
- Jacques Simard,
- Douglas F. Easton,
- Stephen B. Gruber,
- Paul D. P. Pharoah,
- Alkes L. Price,
- Bogdan Pasaniuc,
- Christopher I. Amos,
- Peter Kraft,
- Sara Lindström
Affiliations
- Xia Jiang
- Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health
- Hilary K. Finucane
- Department of Epidemiology, Harvard T.H. Chan School of Public Health
- Fredrick R. Schumacher
- Department of Population and Quantitative Health Sciences, Case Western Reserve University
- Stephanie L. Schmit
- Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute
- Jonathan P. Tyrer
- Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge
- Younghun Han
- Department of Biomedical Data Science, The Geisel School of Medicine at Dartmouth
- Kyriaki Michailidou
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Corina Lesseur
- Genetic Epidemiology Group, International Agency for Research on Cancer
- Karoline B. Kuchenbaecker
- Division of Psychiatry, University College London
- Joe Dennis
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- David V. Conti
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center
- Graham Casey
- Public Health Sciences, University of Virginia
- Mia M. Gaudet
- Epidemiology Research Program, American Cancer Society
- Jeroen R. Huyghe
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Demetrius Albanes
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Melinda C. Aldrich
- Department of Thoracic Surgery, Division of Epidemiology, Vanderbilt University Medical Center
- Angeline S. Andrew
- Department of Neurology, Dartmouth-Hitchcock Medical Center
- Irene L. Andrulis
- Fred ALitwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
- Hoda Anton-Culver
- Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine
- Antonis C. Antoniou
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Natalia N. Antonenkova
- NNAlexandrov Research Institute of Oncology and Medical Radiology, Settlement of Lesnoy-2
- Susanne M. Arnold
- Markey Cancer Center, University of Kentucky
- Kristan J. Aronson
- Department of Public Health Sciences, and Cancer Research Institute, Queen’s University
- Banu K. Arun
- Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center
- Elisa V. Bandera
- Cancer Prevention and Control Program, Rutgers Cancer Institute of New Jersey
- Rosa B. Barkardottir
- Department of Pathology, Landspitali University Hospital
- Daniel R. Barnes
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Jyotsna Batra
- Australian Prostate Cancer Research Centre-Qld, Translational Research Institute
- Matthias W. Beckmann
- Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen Nuremberg, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg
- Javier Benitez
- Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)
- Sara Benlloch
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Andrew Berchuck
- Department of Obstetrics and Gynecology, Duke University Medical Center
- Sonja I. Berndt
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Heike Bickeböller
- Department of Genetic Epidemiology, University Medical Center Goettingen
- Stephanie A. Bien
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Carl Blomqvist
- Department of Oncology, Helsinki University Hospital, University of Helsinki
- Stefania Boccia
- Fondazione Policlinico Universitario A. Gemelli IRCCS
- Natalia V. Bogdanova
- NNAlexandrov Research Institute of Oncology and Medical Radiology, Settlement of Lesnoy-2
- Stig E. Bojesen
- Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital
- Manjeet K. Bolla
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Hiltrud Brauch
- DrMargarete Fischer-Bosch-Institute of Clinical Pharmacology
- Hermann Brenner
- German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ)
- James D. Brenton
- Cancer Research UK Cambridge Institute, University of Cambridge
- Mark N. Brook
- Division of Genetics and Epidemiology, The Institute of Cancer Research
- Joan Brunet
- Genetic Counseling Unit, Hereditary Cancer Program, IDIBGI (Institut d’Investigació Biomèdica de Girona), Catalan Institute of Oncology, CIBERONC
- Hans Brunnström
- Clinical Sciences, Lund University
- Daniel D. Buchanan
- University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre
- Barbara Burwinkel
- Department of Obstetrics and Gynecology, University of Heidelberg
- Ralf Butzow
- Department of Pathology, University of Helsinki and Helsinki University Hospital
- Gabriella Cadoni
- Fondazione Policlinico Universitario A. Gemelli IRCCS
- Trinidad Caldés
- Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC)
- Maria A. Caligo
- Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa
- Ian Campbell
- Peter MacCallum Cancer Center
- Peter T. Campbell
- Epidemiology Research Program, American Cancer Society
- Géraldine Cancel-Tassin
- Sorbonne Université
- Lisa Cannon-Albright
- Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine
- Daniele Campa
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)
- Neil Caporaso
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- André L. Carvalho
- Molecular Oncology Research Center, Barretos Cancer Hospital
- Andrew T. Chan
- Division of Gastroenterology, Massachusetts General Hospital
- Jenny Chang-Claude
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)
- Stephen J. Chanock
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Chu Chen
- Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center
- David C. Christiani
- Department of Epidemiology, Harvard T.H. Chan School of Public Health
- Kathleen B. M. Claes
- Centre for Medical Genetics, Ghent University
- Frank Claessens
- Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven
- Judith Clements
- Australian Prostate Cancer Research Centre-Qld, Translational Research Institute
- J. Margriet Collée
- Department of Clinical Genetics, Erasmus University Medical Center
- Marcia Cruz Correa
- University of Puerto Rico Medical Sciences Campus and Comprehensive Cancer Center
- Fergus J. Couch
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Angela Cox
- Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield
- Julie M. Cunningham
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Cezary Cybulski
- International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University
- Kamila Czene
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Mary B. Daly
- Department of Clinical Genetics, Fox Chase Cancer Center
- Anna deFazio
- Centre for Cancer Research, The Westmead Institute for Medical Research, The University of Sydney
- Peter Devilee
- Department of Pathology, Leiden University Medical Center
- Orland Diez
- Oncogenetics Group, Clinical and Molecular Genetics Area, Vall d’Hebron Institute of Oncology (VHIO), University Hospital
- Manuela Gago-Dominguez
- Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS
- Jenny L. Donovan
- School of Social and Community Medicine, University of Bristol
- Thilo Dörk
- Gynaecology Research Unit, Hannover Medical School
- Eric J. Duell
- Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL)
- Alison M. Dunning
- Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge
- Miriam Dwek
- Department of Biomedical Sciences, Faculty of Science and Technology, University of Westminster
- Diana M. Eccles
- Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton
- Christopher K. Edlund
- Department of Medicine, Keck School of Medicine, University of Southern California
- Digna R Velez Edwards
- Vanderbilt Epidemiology Center, Vanderbilt Genetics Institute, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center
- Carolina Ellberg
- Department of Cancer Epidemiology, Clinical Sciences, Lund University
- D. Gareth Evans
- Manchester Centre for Genomic Medicine, Division of Evolution and Genomic Sciences, University of Manchester, St Mary’s Hospital, Central Manchester University Hospitals NHS Foundation Trust
- Peter A. Fasching
- Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen Nuremberg, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg
- Robert L. Ferris
- Department of Otolaryngology, UPMC Hillman Cancer Center, Cancer Pavilion, University of Pittsburgh
- Triantafillos Liloglou
- Molecular and Clinical Cancer Medicine, Roy Castle Lung Cancer Research Programme, The University of Liverpool Institute of Translational Medicine
- Jane C. Figueiredo
- Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Olivia Fletcher
- The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research
- Renée T. Fortner
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)
- Florentia Fostira
- Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research ‘Demokritos’
- Silvia Franceschi
- Section of Infections, International Agency for Research on Cancer
- Eitan Friedman
- The Susanne Levy Gertner Oncogenetics Unit, Chaim Sheba Medical Center
- Steven J. Gallinger
- Department of Surgery, Mount Sinai Hospital
- Patricia A. Ganz
- Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Centre
- Judy Garber
- Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute
- José A. García-Sáenz
- Medical Oncology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos (IdISSC), Centro Investigación Biomédica en Red de Cáncer (CIBERONC)
- Simon A. Gayther
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Graham G. Giles
- Cancer Epidemiology & Intelligence Division, Cancer Council Victoria
- Andrew K. Godwin
- Department of Pathology and Laboratory Medicine, University of Kansas Medical Center
- Mark S. Goldberg
- Department of Medicine, McGill University
- David E. Goldgar
- Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine
- Ellen L. Goode
- Department of Health Sciences Research, Mayo Clinic
- Marc T. Goodman
- Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Gary Goodman
- Public Health Sciences Division, Swedish Cancer Institute
- Kjell Grankvist
- Unit of Clinical Chemistry, Department of Medical Biosciences, Umeå University
- Mark H. Greene
- Clinical Genetics Branch, National Cancer Institute, DCEG
- Henrik Gronberg
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Jacek Gronwald
- International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University
- Pascal Guénel
- Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay
- Niclas Håkansson
- Department of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet
- Per Hall
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Ute Hamann
- Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)
- Freddie C. Hamdy
- Nuffield Department of Surgical Sciences, Faculty of Medical Science, John Radcliffe Hospital, University of Oxford
- Robert J. Hamilton
- Department of Surgical Oncology, Princess Margaret Cancer Centre
- Jochen Hampe
- Department of Internal Medicine 1, University Hospital Dresden, Technische Universität Dresden (TU Dresden)
- Aage Haugen
- National Institute of Occupational Health (STAMI)
- Florian Heitz
- Department of Gynecology and Gynecologic Oncology, DrHorst Schmidt Kliniken Wiesbaden
- Rolando Herrero
- Early Detection and Prevention Section, International Agency for Research on Cancer
- Peter Hillemanns
- Gynaecology Research Unit, Hannover Medical School
- Michael Hoffmeister
- Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)
- Estrid Høgdall
- Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center
- Yun-Chul Hong
- Preventive Medicine, Seoul National University College of Medicine
- John L. Hopper
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health
- Richard Houlston
- German Research Center for Environmental Health, Institute for Cancer Research
- Peter J. Hulick
- Center for Medical Genetics, NorthShore University HealthSystem
- David J. Hunter
- Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health
- David G. Huntsman
- British Columbia’s Ovarian Cancer Research (OVCARE) Program, Vancouver General Hospital, BC Cancer Agency and University of British Columbia
- Gregory Idos
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center
- Evgeny N. Imyanitov
- NNPetrov Institute of Oncology
- Sue Ann Ingles
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center
- Claudine Isaacs
- Lombardi Comprehensive Cancer Center, Georgetown University
- Anna Jakubowska
- International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University
- Paul James
- Sir Peter MacCallum Department of Oncology, The University of Melbourne
- Mark A. Jenkins
- University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre
- Mattias Johansson
- Section of Genetics, International Agency for Research on Cancer
- Mikael Johansson
- Department of Radiation Sciences, Umeå University
- Esther M. John
- Department of Medicine, Division of Oncology and Stanford Cancer Institute, Stanford University School of Medicine
- Amit D. Joshi
- Department of Epidemiology, Harvard T.H. Chan School of Public Health
- Radka Kaneva
- Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia
- Beth Y. Karlan
- Women’s Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Linda E. Kelemen
- Hollings Cancer Center and Department of Public Health Sciences, Medical University of South Carolina
- Tabea Kühl
- Cancer Epidemiology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf
- Kay-Tee Khaw
- Clinical Gerontology, Department of Public Health and Primary Care, University of Cambridge
- Elza Khusnutdinova
- Department of Genetics and Fundamental Medicine, Bashkir State University
- Adam S. Kibel
- Division of Urologic Surgery, Brigham and Womens Hospital
- Lambertus A. Kiemeney
- Radboud Institute for Health Sciences, Radboud University Medical Center
- Jeri Kim
- Department of Genitourinary Medical Oncology, University of Texas MD Anderson Cancer Center
- Susanne K. Kjaer
- Department of Virus, Lifestyle and Genes, Danish Cancer Society Research Center
- Julia A. Knight
- Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System
- Manolis Kogevinas
- Biomedical Network on Rare Diseases (CIBERER), AvMonforte de Lemos
- Zsofia Kote-Jarai
- Division of Genetics and Epidemiology, The Institute of Cancer Research
- Stella Koutros
- Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, National Institutes of Health
- Vessela N. Kristensen
- Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet
- Jolanta Kupryjanczyk
- Department of Pathology and Laboratory Diagnostics, the Maria Sklodowska-Curie Institute - Oncology Center
- Martin Lacko
- Head and Neck Surgery, Department of Otorhinolaryngology, Maastricht University Medical Center
- Stephan Lam
- Department of Integrative Oncology, British Columbia Cancer Agency
- Diether Lambrechts
- VIB Center for Cancer Biology, VIB
- Maria Teresa Landi
- Integrative Tumor Epidemiology Branch, DCEG, National Cancer Institute
- Philip Lazarus
- College of Pharmacy, Washington State University
- Nhu D. Le
- Cancer Control Research, BC Cancer Agency
- Eunjung Lee
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Flavio Lejbkowicz
- Clalit Health Services, Clalit National Israeli Cancer Control Center, Carmel Medical Center
- Heinz-Josef Lenz
- Department of Medicine, Keck School of Medicine, University of Southern California
- Goska Leslie
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Davor Lessel
- Institute of Human Genetics, University Medical Center Hamburg-Eppendorf
- Jenny Lester
- Women’s Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Douglas A. Levine
- Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center
- Li Li
- Department of Family Medicine and Community Health, Mary Ann Swetland Center for Environmental Health, Case Western Reserve University
- Christopher I. Li
- Translational Research Program, Fred Hutchinson Cancer Research Center
- Annika Lindblom
- Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska Univ Hospital
- Noralane M. Lindor
- Health Sciences Research, Mayo Clinic Arizona
- Geoffrey Liu
- Epidemiology Division, Princess Margaret Cancer Centre
- Fotios Loupakis
- Unit of Oncology 1, Department of Clinical and Experimental Oncology, Istituto Oncologico Veneto IRCCS
- Jan Lubiński
- International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University
- Lovise Maehle
- Department of Medical Genetics, Oslo University Hospital
- Christiane Maier
- Institute of Human Genetics, University Hospital Ulm
- Arto Mannermaa
- Translational Cancer Research Area, University of Eastern Finland
- Loic Le Marchand
- Epidemiology Program, University of Hawaii Cancer Center
- Sara Margolin
- Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet
- Taymaa May
- Division of Gynecologic Oncology, University Health Network, Princess Margaret Hospital
- Lesley McGuffog
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Alfons Meindl
- Division of Gynaecology and Obstetrics, , Technische Universität München
- Pooja Middha
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)
- Austin Miller
- NRG Oncology, Statistics and Data Management Center, Roswell Park Cancer Institute
- Roger L. Milne
- Cancer Epidemiology & Intelligence Division, Cancer Council Victoria
- Robert J. MacInnis
- Cancer Epidemiology & Intelligence Division, Cancer Council Victoria
- Francesmary Modugno
- Womens Cancer Research Center, Magee-Womens Research Institute and Hillman Cancer Center
- Marco Montagna
- Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS
- Victor Moreno
- Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP) and University of Barcelona
- Kirsten B. Moysich
- Division of Cancer Prevention and Control, Roswell Park Cancer Institute
- Lorelei Mucci
- Department of Epidemiology, Harvard T.H. Chan School of Public Health
- Kenneth Muir
- Division of Population Health, Health Services Research and Primary Care, University of Manchester
- Anna Marie Mulligan
- Department of Laboratory Medicine and Pathobiology, University of Toronto
- Katherine L. Nathanson
- Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania
- David E. Neal
- Cancer Research UK Cambridge Institute, University of Cambridge
- Andrew R. Ness
- NIHR Bristol Biomedical Research Centre Nutrition Theme, University of Bristol
- Susan L. Neuhausen
- Department of Population Sciences, Beckman Research Institute of City of Hope
- Heli Nevanlinna
- Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki
- Polly A. Newcomb
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Lisa F. Newcomb
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Finn Cilius Nielsen
- Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital
- Liene Nikitina-Zake
- Latvian Biomedical Research and Study Centre
- Børge G. Nordestgaard
- Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital
- Robert L. Nussbaum
- Cancer Genetics and Prevention Program, University of California San Francisco
- Kenneth Offit
- Clinical Genetics Research Lab, Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center
- Edith Olah
- Department of Molecular Genetics, National Institute of Oncology
- Ali Amin Al Olama
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Olufunmilayo I. Olopade
- Center for Clinical Cancer Genetics, The University of Chicago
- Andrew F. Olshan
- Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina
- Håkan Olsson
- Department of Cancer Epidemiology, Clinical Sciences, Lund University
- Ana Osorio
- Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO)
- Hardev Pandha
- The University of Surrey
- Jong Y. Park
- Department of Cancer Epidemiology, HLee Moffitt Cancer Center and Research Institute
- Nora Pashayan
- Department of Applied Health Research, University College London
- Michael T. Parsons
- Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute
- Tanja Pejovic
- Department of Obstetrics and Gynecology, Oregon Health & Science University
- Kathryn L. Penney
- Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School
- Wilbert H M. Peters
- Department of Gastroenterology, Radboud University Nijmegen Medical Center
- Catherine M. Phelan
- Department of Cancer Epidemiology, HLee Moffitt Cancer Center and Research Institute
- Amanda I. Phipps
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Dijana Plaseska-Karanfilska
- Research Centre for Genetic Engineering and Biotechnology ‘Georgi DEfremov’, Macedonian Academy of Sciences and Arts
- Miranda Pring
- Bristol Dental School, University of Bristol
- Darya Prokofyeva
- Department of Genetics and Fundamental Medicine, Bashkir State University
- Paolo Radice
- Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS (Istituto Di Ricovero e Cura a Carattere Scientifico) Istituto Nazionale dei Tumori (INT)
- Kari Stefansson
- Decode genetics
- Susan J. Ramus
- School of Women’s and Children’s Health, Faculty of Medicine, University of NSW Sydney
- Leon Raskin
- Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine
- Gad Rennert
- Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine
- Hedy S. Rennert
- Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine
- Elizabeth J. van Rensburg
- Department of Genetics, University of Pretoria
- Marjorie J. Riggan
- Department of Obstetrics and Gynecology, Duke University Medical Center
- Harvey A. Risch
- Department of Chronic Disease Epidemiology, Yale School of Public Health
- Angela Risch
- Cancer Center Cluster Salzburg at PLUS, Department of Molecular Biology, University of Salzburg
- Monique J. Roobol
- Department of Urology, Erasmus University Medical Center
- Barry S. Rosenstein
- Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai
- Mary Anne Rossing
- Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center
- Kim De Ruyck
- Faculty of Medicine and Health Sciences, Basic Medical Sciences, Ghent University
- Emmanouil Saloustros
- Hereditary Cancer Clinic, University Hospital of Heraklion
- Dale P. Sandler
- Epidemiology Branch, National Institute of Environmental Health Sciences
- Elinor J. Sawyer
- Research Oncology, Guy’s Hospital, King’s College London, Guy’s Hospital Great Maze Pond
- Matthew B. Schabath
- Department of Cancer Epidemiology, HLee Moffitt Cancer Center and Research Institute
- Johanna Schleutker
- Institute of Biomedicine, University of Turku
- Marjanka K. Schmidt
- Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital
- V. Wendy Setiawan
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Hongbing Shen
- Department of Epidemiology and Biostatistics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University
- Erin M. Siegel
- Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute
- Weiva Sieh
- Department of Genetics and Genomic Sciences, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai
- Christian F. Singer
- Dept of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna
- Martha L. Slattery
- Department of Internal Medicine, University of Utah Health Sciences Center
- Karina Dalsgaard Sorensen
- Department of Molecular Medicine, Aarhus University Hospital
- Melissa C. Southey
- Precision Medicine, School of Clinical Sciences at Monash Health, Monash University
- Amanda B. Spurdle
- Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute
- Janet L. Stanford
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Victoria L. Stevens
- Epidemiology Research Program, American Cancer Society
- Sebastian Stintzing
- Department of Medicine III, University Hospital, LMU Munich
- Jennifer Stone
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health
- Karin Sundfeldt
- Department of Obstetrics and Gynecology, Sahlgrenska Cancer Center, Inst Clinical Scienses, University of Gothenburg
- Rebecca Sutphen
- Epidemiology Center, College of Medicine, University of South Florida
- Anthony J. Swerdlow
- Division of Genetics and Epidemiology, The Institute of Cancer Research
- Eloiza H. Tajara
- Department of Molecular Biology, School of Medicine of São José do Rio Preto
- Catherine M. Tangen
- SWOG Statistical Center, Fred Hutchinson Cancer Research Center
- Adonina Tardon
- Faculty of Medicine, University of Oviedo and CIBERESP
- Jack A. Taylor
- Epidemiology Branch, National Institute of Environmental Health Sciences
- M. Dawn Teare
- Medical Statistics Group, School of Health and Related Research (ScHARR), University of Sheffield
- Manuel R. Teixeira
- Department of Genetics, Portuguese Oncology Institute
- Mary Beth Terry
- Department of Epidemiology, Mailman School of Public Health, Columbia University
- Kathryn L. Terry
- Obstetrics and Gynecology Epidemiology Center, Brigham and Women’s Hospital
- Stephen N. Thibodeau
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Mads Thomassen
- Department of Clinical Genetics, Odense University Hospital
- Line Bjørge
- Department of Gynecology and Obstetrics, Haukeland University Hospital
- Marc Tischkowitz
- Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University
- Amanda E. Toland
- Department of Cancer Biology and Genetics, The Ohio State University
- Diana Torres
- Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)
- Paul A. Townsend
- Division of Cancer Sciences, Manchester Cancer Research Centre, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, NIHR Manchester Biomedical Research Centre, Health Innovation Manchester, University of Manchester
- Ruth C. Travis
- Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford
- Nadine Tung
- Department of Medical Oncology, Beth Israel Deaconess Medical Center
- Shelley S. Tworoger
- Department of Epidemiology, Harvard T.H. Chan School of Public Health
- Cornelia M. Ulrich
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Nawaid Usmani
- Department of Oncology, Cross Cancer Institute, University of Alberta
- Celine M. Vachon
- Department of Health Sciences Research, Mayo Clinic
- Els Van Nieuwenhuysen
- Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven
- Ana Vega
- Biomedical Network on Rare Diseases (CIBERER), AvMonforte de Lemos
- Miguel Elías Aguado-Barrera
- Fundación Pública Galega Medicina Xenómica & Instituto de Investigación Sanitaria de Santiago de Compostela, calle Choupana s/n
- Qin Wang
- Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
- Penelope M. Webb
- Population Health Department, QIMR Berghofer Medical Research Institute
- Clarice R. Weinberg
- Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH
- Stephanie Weinstein
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Mark C. Weissler
- Department of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill
- Jeffrey N. Weitzel
- City of Hope Clinical Cancer Genomics Community Research Network
- Catharine M. L. West
- Division of Cancer Sciences, University of Manchester, Manchester Cancer Research Centre, Manchester Academic Health Science Centre,, The Christie Hospital NHS Foundation Trust
- Emily White
- Fred Hutchinson Cancer Research Center
- Alice S. Whittemore
- Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine
- H-Erich Wichmann
- Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig Maximilians University
- Fredrik Wiklund
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Robert Winqvist
- Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu
- Alicja Wolk
- Department of Environmental Medicine, Division of Nutritional Epidemiology, Karolinska Institutet
- Penella Woll
- Academic Unit of Clinical Oncology, University of Sheffield
- Michael Woods
- Discipline of Genetics, Memorial University of Newfoundland
- Anna H. Wu
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Xifeng Wu
- Department of Epidemiology, Division of Cancer Prevention and Population Science, The University of Texas MD Anderson Cancer Center
- Drakoulis Yannoukakos
- Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research ‘Demokritos’
- Wei Zheng
- Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine
- Shanbeh Zienolddiny
- National Institute of Occupational Health (STAMI)
- Argyrios Ziogas
- Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine
- Kristin K. Zorn
- Magee-Womens Hospital, University of Pittsburgh School of Medicine
- Jacqueline M. Lane
- Program in Medical and Population Genetics, Broad Institute of MIT and Harvard
- Richa Saxena
- Program in Medical and Population Genetics, Broad Institute of MIT and Harvard
- Duncan Thomas
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Rayjean J. Hung
- Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System
- Brenda Diergaarde
- Human Genetics, Graduate School of Public Health, University of Pittsburgh
- James McKay
- Genetic Cancer Susceptibility Group, International Agency for Research on Cancer
- Ulrike Peters
- Department of Epidemiology, University of Washington School of Public Health
- Li Hsu
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- Montserrat García-Closas
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Rosalind A. Eeles
- Division of Genetics and Epidemiology, The Institute of Cancer Research
- Georgia Chenevix-Trench
- Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute
- Paul J. Brennan
- Section of Genetics, International Agency for Research on Cancer
- Christopher A. Haiman
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center
- Jacques Simard
- Genomics Center, Centre Hospitalier Universitaire de Québec - Université Laval Research Center
- Douglas F. Easton
- Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge
- Stephen B. Gruber
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California
- Paul D. P. Pharoah
- Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge
- Alkes L. Price
- Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health
- Bogdan Pasaniuc
- UCLA Path and Lab Med, University of California
- Christopher I. Amos
- Department of Medicine, Epidemiology Section, Institute for Clinical and Translational Research, Baylor Medical College
- Peter Kraft
- Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health
- Sara Lindström
- Public Health Sciences Division, Fred Hutchinson Cancer Research Center
- DOI
- https://doi.org/10.1038/s41467-018-08054-4
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 23
Abstract
Similarities in cancers can be studied to interrogate their etiology. Here, the authors use genome-wide association study summary statistics from six cancer types based on 296,215 cases and 301,319 controls of European ancestry, showing that solid tumours arising from different tissues share a degree of common germline genetic basis.
