Decoding the stoichiometric composition and organisation of bacterial metabolosomes

Mengru Yang; Deborah M. Simpson; Nicolas Wenner; Philip Brownridge; Victoria M. Harman; Jay C. D. Hinton; Robert J. Beynon; Lu-Ning Liu

doi:10.1038/s41467-020-15888-4

Nature Communications (Apr 2020)

Decoding the stoichiometric composition and organisation of bacterial metabolosomes

Mengru Yang,
Deborah M. Simpson,
Nicolas Wenner,
Philip Brownridge,
Victoria M. Harman,
Jay C. D. Hinton,
Robert J. Beynon,
Lu-Ning Liu

Affiliations

Mengru Yang: Institute of Integrative Biology, University of Liverpool
Deborah M. Simpson: Institute of Integrative Biology, University of Liverpool
Nicolas Wenner: Institute of Integrative Biology, University of Liverpool
Philip Brownridge: Institute of Integrative Biology, University of Liverpool
Victoria M. Harman: Institute of Integrative Biology, University of Liverpool
Jay C. D. Hinton: Institute of Integrative Biology, University of Liverpool
Robert J. Beynon: Institute of Integrative Biology, University of Liverpool
Lu-Ning Liu: Institute of Integrative Biology, University of Liverpool

DOI: https://doi.org/10.1038/s41467-020-15888-4
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 11

Abstract

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Enteric pathogens such as Salmonella depend on propanediol-utilising microcompartments (Pdu MCP), which self-assemble from cytosolic proteins. Using mass spectrometry-based absolute quantification, the authors here define the protein stoichiometry and propose an organizational model of a Salmonella Pdu MCP.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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