Foods (Mar 2023)

The Anti-Fatigue Effect of Glycoprotein from Hairtail Fish (<i>Trichiurus lepturus</i>) on BALB/c Mice

  • Xiaodan Lu,
  • Jiaqi Chen,
  • Luyao Huang,
  • Yujia Ou,
  • Jingru Wu,
  • Zebin Guo,
  • Baodong Zheng

DOI
https://doi.org/10.3390/foods12061245
Journal volume & issue
Vol. 12, no. 6
p. 1245

Abstract

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Fatigue is related to a variety of chronic diseases and has become a hot research topic in recent years. Various bioactive components have been extracted from hairtail fish (Trichiurus lepturus); however, none of these studies involved the anti-fatigue activity of hairtail fish glycoprotein (HGP). Thus, antioxidant experiments were conducted in vitro, and the anti-fatigue activity of HGP was further evaluated in BALB/c mice. The effects of HGP on the behavior of BALB/c mice were verified by classical behavioral experiments, and the indicators related to anti-fatigue activity were detected. The results showed that the antioxidant capacity in vitro of HGP increased gradually in the concentration range of 10 to 100 mg/mL. HGP improved the exercise ability of the mice. HGP was also found to significantly (p p p p < 0.05) increased by HGP, especially in the middle- and high-dose groups. These results enhance our understanding of the anti-fatigue function of HGP and lay an important foundation for the further development and utilization of hairtail fish resources.

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