Journal of Investigative Medicine High Impact Case Reports (Dec 2023)

A Case of Adrenocortical Carcinoma With a Favorable Tumor Control by Radiofrequency Ablation for Liver Metastasis

  • Kensuke Kitsugi MD,
  • Kazuhito Kawata MD, PhD,
  • Keisuke Kakizawa MD, PhD,
  • Hidenao Noritake MD, PhD

DOI
https://doi.org/10.1177/23247096231218135
Journal volume & issue
Vol. 11

Abstract

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A 57-year-old woman was diagnosed with adrenocortical carcinoma. Following the adrenalectomy, she underwent adjuvant radiation and mitotane therapy; however, liver metastases were observed. Repeated radiofrequency ablation (RFA) was performed for liver metastases. In addition, a multidisciplinary approach combining systemic chemotherapy, radiotherapy, and surgery was used for lung and distant lymph node metastases that arose during the course of treatment. Notably, 49 months have passed since the adrenalectomy and 36 months since the recurrence of the liver metastases, and the patient remains on multidisciplinary therapy. Thus, RFA for liver metastasis of adrenocortical carcinoma may be an effective component of a multidisciplinary treatment.