Çukurova Üniversitesi Tıp Fakültesi Dergisi (Apr 2014)

Hypokalemic paralysis and respiratory failure due to excessive intake of licorice syrup

  • Mehmet Oguzhan Ay,
  • Abdulkadir Akturk,
  • Ahmet Colakoglu,
  • Alper Celikdemir,
  • Nalan Kozaci,
  • Ayca Acikalin,
  • Akkan Avci,
  • Salim Satar

Journal volume & issue
Vol. 39, no. 2
pp. 387 – 391

Abstract

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Licorice is the root of Glycyrrhiza glabra, which has a herbal ingredient, glycyrrhizic acid. Excessive intake of licorice may cause a hypermineralocorticoidism-like syndrome characterized by sodium and water retention, hypokalemia, hypertension, metabolic alkalosis, low-renin activity, and hypoaldosteronism. In this paper, an 34 years old man who admitted to the emergency department with respiratory failure and marked muscle weakness of all extremities that progressed to paralysis after excessive intake of licorice syrup was presented. It was aimed to draw attention to the necessity of questioning whether there is excessive intake of licorice or not in patients who admitted to emergency department with paralysis and dyspnea. Plasma potassium concentration of the patient was 1.4 mmol/L. The patient\'s respiratory distress and loss of muscle strength recovered completely after potassium replacement. [Cukurova Med J 2014; 39(2.000): 387-391]

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