Germline and somatic genetic alterations in two first‐degree relatives with appendiceal low‐grade mucinous carcinoma peritonei

Abstract

Abstract Comparing genetic mutations of first‐degree relatives with appendiceal pseudomyxoma peritonei may explain clinical outcomes and disease pathogenesis. Molecular profiling of mucinous tumors may identify improved treatments to traditional chemotherapy.

Keywords

• appendix cancer
• genetic analysis
• hyperthermic intraperitoneal chemotherapy
• next‐generation sequencing
• pseudomyxoma peritonei