The whole molecule of the title compound, C16H20N2O8, is generated by inversion symmetry. The adjacent carboxylate groups [C(=O)—O—C] are inclined to the pyrazine ring by 72.40 (10) and 19.64 (10)°, and to one another by 68.21 (12)°. In the crystal, molecules stack along the a-axis direction but there are no significant intermolecular interactions present.