Journal of Applied Biomaterials & Functional Materials (Nov 2021)

Nanodesigned coatings obtained by plasma electrolytic oxidation of titanium implant and their cytotoxicity

  • Marko Magić,
  • Božana Čolović,
  • Saša Vasilijić,
  • Nenad Tadić,
  • Stevan Stojadinović,
  • Vukoman Jokanović

DOI
https://doi.org/10.1177/2280800018822252
Journal volume & issue
Vol. 19

Abstract

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The titanium implant was treated with plasma electrolytic oxidation and subsequent ionic exchange and thermal treatment in order to obtain bioactive layer consisting of titanium oxide, calcium and sodium titanates and hydroxyapatite, as confirmed by X-ray diffraction (XRD). Scanning electron microscopy (SEM) revealed that the given method, besides corresponding phase composition, enables suitable nanotopology for cell attachment and proliferation. Cytotoxicity investigations by MTT, LDH and propidium iodide assays and light microscopy showed that these coatings were not toxic to L929 cells.