Osobennosti funktsional'nogo sostoyaniyakory nadpochechnikov i shchitovidnoy zhelezypri metabolicheskom sindrome

Abstract

The aim. To study the functional state of adrenal cortex and thyroid gland in metabolic syndrome (MS). 186 women and 65 men were included. Blood levels of cortisol, dehydroepiandrosterone sulphate, total thyroxin, total triiodothyronine, thyroid stimulating hormone were studied in subjects with and without metabolic syndrome (IDF test) and their relation with MS components. The results. 75 (29,9%) of the 251 examined patients had MS. In the group with MS the levels of total thyroxin and dehydroepiandrosterone sulphate were decreased to 1,90±0,18 microgram/milliliter vs. 2,37±0,12 microgram/milliliter (р=0,033) in patients without MS and 2,19±0,26 nmol/l vs. 2,59±0,15 nmol/l (р=0,040), respectively. The levels of dehydroepiandrosterone sulphate were inversely correlated with the systolic blood pressure (r=-0,23, р

Keywords

• metabolic syndrome
• dehydroepiandrosterone sulphate
• triiodothyronine
• thyroid gland