Marbofloxacin

Abstract

In the title compound, [systematic name: 9-fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid], C17H19FN4O4, the carbonyl and carboxyl groups are coplanar with the quinoline ring, making a dihedral angle of 2.39 (2)°. The piperazine ring adopts a chair conformation and the oxadiazinane ring displays an envelope conformation with the CH2 group at the flap displaced by 0.650 (2) Å from the plane through the other five atoms. The molecular structure exhibits an S(6) ring motif, owing to an intramolecular O—H...O hydrogen bond. In the crystal, weak C—H...F hydrogen bonds link molecules into layers parallel to the ab plane.