Irritable bowel syndrome: epidemiological and pathogenetic aspects

Abstract

The literature review focuses on some epidemiological aspects, molecular-genetic predictors of irritable bowel syndrome formation, the role of psychosocial and infectious factors, low-grade inflammation, imbalance between neu-rotransmitters and cytokines, as well as changes in the intestinal microbiome in the development of irritable bowel syndrome.

Keywords

• genetic markers
• inflammation
• irritable bowel syndrome (IBS)
• microbiome