Frontiers in Pediatrics (Mar 2022)

Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant

  • Fabian J. S. van der Velden,
  • Fabian J. S. van der Velden,
  • Frederik van Delft,
  • Stephen Owens,
  • Judit Llevadias,
  • Michael McKean,
  • Lindsey Pulford,
  • Yusri Taha,
  • Grace Williamson,
  • Quentin Campbell-Hewson,
  • Sophie Hambleton,
  • Sophie Hambleton,
  • Rebecca Payne,
  • Christopher Duncan,
  • Christopher Duncan,
  • Catriona Johnston,
  • Jarmila Spegarova,
  • Marieke Emonts,
  • Marieke Emonts

DOI
https://doi.org/10.3389/fped.2022.809061
Journal volume & issue
Vol. 10

Abstract

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Pulmonary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is generally described as mild, and SARS-CoV-2 infection in immunocompromised children are observed as generally mild as well. A small proportion of pediatric patients will become critically ill due to (cardio)respiratory failure and require intensive care treatment. We report the case of a teenager with Hodgkin's lymphoma who acquired SARS-CoV-2 (detected by PCR) on the day of her autologous stem cell transplant and developed acute respiratory distress syndrome, successfully treated with a combination of antivirals, immunomodulation with steroids and biologicals, and ECMO.

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