6-Cyclohexylmethyl-5-ethyl-2-[(2-oxo-2-phenylethyl)sulfanyl]pyrimidin-4(3H)-one

Abstract

In the title compound, C21H26N2O2S, the cyclohexane ring adopts a chair conformation. The angle at the methylene bridge linking the pyrimidine and cyclohexane rings is 113.41 (13)°. This is in the range considered optimal for maximum activity of non-nucleoside reverse transcriptase inhibitors. In the crystal, molecules are connected into centrosymmetric dimers via pairs of N—H...O hydrogen bonds.