Radiology Case Reports (Oct 2023)

Invasive candidiasis presenting bronchiectatic cavity as chest radiological findings: A case report

  • Atsuhiro Ijiri, MD,
  • Takero Terayama, MD, PhD,
  • Hiroaki Sugiura, MD, PhD,
  • Mayuko Kaneko, MD,
  • Soichiro Seno, MD, PhD,
  • Nobuaki Kiriu, MD,
  • Hiroshi Kato, MD,
  • Yasumasa Sekine, MD, PhD,
  • Hiroshi Shinmoto, MD, PhD,
  • Tetsuro Kiyozumi, MD, PhD

Journal volume & issue
Vol. 18, no. 10
pp. 3467 – 3470

Abstract

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Invasive candidiasis is rare but is associated with high mortality in immunocompromised or critically ill patients. Here, we present a case of a 55-year-old man with untreated diabetes who was diagnosed with coronavirus disease 2019 and subsequently developed invasive candidiasis. The patient presented with fever, tachycardia, and tachypnea. Chest computed tomography revealed multiple consolidations mainly distributed around the bronchovascular bundles with bronchiectatic cavity formation, which initially raised suspicion for invasive pulmonary aspergillosis. However, subsequent testing confirmed Candida albicans infection; hence, we changed the antifungal agents effective for invasive candidiasis. This improved the patient's respiratory status, and he was then successfully weaned from mechanical ventilation. This case report highlights the importance of considering invasive candidiasis in the differential diagnosis of patients with bronchiectatic cavities on chest computed tomography, particularly in immunocompromised or critically ill patients with risk factors for invasive candidiasis.

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