Кардиоваскулярная терапия и профилактика (Mar 2019)

Supply of vitamins for patients with type 2 diabetes and obesity in the autumn

  • N. A. Beketova,
  • O. V. Kosheleva,
  • O. A. Vrzhesinskaya,
  • V. M. Kodentsova,
  • H. H. Sharafetdinov,
  • O. A. Plotnikova,
  • V. V. Pilipenko,
  • R. I. Alekseeva,
  • S. N. Leonenko,
  • A. A. Sokolnikov

DOI
https://doi.org/10.15829/1728-8800-2019-1-95-101
Journal volume & issue
Vol. 18, no. 1
pp. 95 – 101

Abstract

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Aim. To assess the availability of patients with type 2 diabetes mellitus (DM-2) and obesity with vitamins C, A, E, D, B2, B6, niacin and betacarotene.Material and methods. We assess vitamin status of 40 patients with DM-2 (14 men and 26 women) aged 42-80 years was 60,2±1,3 (Me=60,5) with concomitant obesity and a body mass index from 31,2 to 57,4 kg 42,1±1,1 (Me=42,0), receiving oral hypoglycemic therapy. The disease duration ranged from six months to 32 years — 7,4±1,0 (Me=6,0), the level of glycohemoglobin — from 5,20% to 7,70% — 6,27±0,11 (Me=6,05). The provision of C, A, E, D, B2 vitamins and beta-carotene was assessed by their serum concentration, B6 and niacin vitamins — by excretion of their metabolites with urine.Results. Against the background of a good supply of patients with A, E, C and PP vitamins, a reduced serum concentration of 25-OH vitamin D was detected in the majority (83%) of the patients, beta carotene — in 55%, insufficient provision with vitamins B6 and B2 — 15-18%. A reduced serum concentration of 1-2 vitamins was detected in 65% of the patients. A combined deficiency of 3-4 vitamins had 25% of patients.Conclusion. The presence of vitamin deficiencies in patients with DM-2, which are a risk factor for its occurrence and the development of complications, indicates the need to optimize vitamin status. The negative association between the level of basal glycemia in venous blood and glucosuria and the concentration of γ-tocopherol may indicate certain benefits of using dietary oils with a high level of vitamer.

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