Visualisation of DCP, a nerve agent mimic, in Catfish brain by a simple chemosensor

Himadri Sekhar Sarkar; Ayndrila Ghosh; Sujoy Das; Pulak Kumar Maiti; Sudipta Maitra; Sukhendu Mandal; Prithidipa Sahoo

doi:10.1038/s41598-018-21780-5

Scientific Reports (Feb 2018)

Visualisation of DCP, a nerve agent mimic, in Catfish brain by a simple chemosensor

Himadri Sekhar Sarkar,
Ayndrila Ghosh,
Sujoy Das,
Pulak Kumar Maiti,
Sudipta Maitra,
Sukhendu Mandal,
Prithidipa Sahoo

Affiliations

Himadri Sekhar Sarkar: Department of Chemistry, Visva-Bharati University
Ayndrila Ghosh: Department of Chemistry, Visva-Bharati University
Sujoy Das: Department of Chemistry, Visva-Bharati University
Pulak Kumar Maiti: Department of Microbiology, University of Calcutta
Sudipta Maitra: Department of Zoology, Visva-Bharati University
Sukhendu Mandal: Department of Microbiology, University of Calcutta
Prithidipa Sahoo: Department of Chemistry, Visva-Bharati University

DOI: https://doi.org/10.1038/s41598-018-21780-5
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 7

Abstract

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Abstract A chemosensor, 3-aminophenol-based rhodamine conjugate (ARC) has been developed for visualisation of diethylchlorophosphate (DCP), mimic of a chemical warfare agent, in Catfish brain. The simple detection of DCP by “turn-on” fluorescence property of the chemosensor makes it unique for easy and rapid in vivo and in vitro detection of DCP with the detection limit of 5.6 nM.

Published in Scientific Reports

ISSN: 2045-2322 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Medicine; Science
Website: https://www.nature.com/srep/

About the journal