Nature Communications (May 2022)
Genetic and phylogenetic uncoupling of structure and function in human transmodal cortex
- Sofie L. Valk,
- Ting Xu,
- Casey Paquola,
- Bo-yong Park,
- Richard A. I. Bethlehem,
- Reinder Vos de Wael,
- Jessica Royer,
- Shahrzad Kharabian Masouleh,
- Şeyma Bayrak,
- Peter Kochunov,
- B. T. Thomas Yeo,
- Daniel Margulies,
- Jonathan Smallwood,
- Simon B. Eickhoff,
- Boris C. Bernhardt
Affiliations
- Sofie L. Valk
- Otto Hahn Group Cognitive Neurogenetics, Max Planck Institute for Human Cognitive and Brain Sciences
- Ting Xu
- Center for the Developing Brain, Child Mind Institute
- Casey Paquola
- Multimodal Imaging and Connectome Analysis Lab, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Bo-yong Park
- Multimodal Imaging and Connectome Analysis Lab, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Richard A. I. Bethlehem
- Department of Psychiatry, Cambridge University
- Reinder Vos de Wael
- Multimodal Imaging and Connectome Analysis Lab, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Jessica Royer
- Multimodal Imaging and Connectome Analysis Lab, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- Shahrzad Kharabian Masouleh
- Institute of Neuroscience and Medicine, Brain & Behaviour (INM-7), Research Centre Jülich, FZ Jülich
- Şeyma Bayrak
- Otto Hahn Group Cognitive Neurogenetics, Max Planck Institute for Human Cognitive and Brain Sciences
- Peter Kochunov
- Department of Psychiatry, University of Maryland School of Medicine
- B. T. Thomas Yeo
- Department of Electrical and Computer Engineering, National University of Singapore
- Daniel Margulies
- Neuroanatomy and Connectivity Lab, Institut de Cerveau et de la Moelle epiniere
- Jonathan Smallwood
- Department of Psychology, Queen’s University
- Simon B. Eickhoff
- Institute of Neuroscience and Medicine, Brain & Behaviour (INM-7), Research Centre Jülich, FZ Jülich
- Boris C. Bernhardt
- Multimodal Imaging and Connectome Analysis Lab, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University
- DOI
- https://doi.org/10.1038/s41467-022-29886-1
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 17
Abstract
Brain structure scaffolds intrinsic function, supporting cognition and behavioral flexibility. Here, the authors show how macroscale organization of cortical microstructure and resting-state function uncouple in transmodal cortex of humans and macaques.