Nature Communications (Aug 2017)

Whi7 is an unstable cell-cycle repressor of the Start transcriptional program

  • Mercè Gomar-Alba,
  • Ester Méndez,
  • Inma Quilis,
  • M. Carmen Bañó,
  • J. Carlos Igual

DOI
https://doi.org/10.1038/s41467-017-00374-1
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 13

Abstract

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The commitment of cells to a new cycle of division involves inactivation of the Start transcriptional repressor Whi5. Here the authors show that the sequence related protein Whi7 associates to G1/S gene promoters in late G1 and collaborates with Whi5 in Start repression.