What triggers inflammation in COVID-19?

Tomohiro Sawa; Takaaki Akaike

doi:10.7554/eLife.76231

eLife (Jan 2022)

What triggers inflammation in COVID-19?

Tomohiro Sawa,
Takaaki Akaike

Affiliations

Tomohiro Sawa: ORCiD; Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
Takaaki Akaike: ORCiD; Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan

DOI: https://doi.org/10.7554/eLife.76231
Journal volume & issue: Vol. 11

Abstract

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The spike protein of SARS-CoV-2 triggers macrophages and epithelial cells to produce excess levels of pro-inflammatory molecules, which can do more harm than good.

Published in eLife

ISSN: 2050-084X (Online)
Publisher: eLife Sciences Publications Ltd
Country of publisher: United Kingdom
LCC subjects: Medicine; Science: Biology (General)
Website: https://elifesciences.org

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Abstract

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