Frontiers in Veterinary Science (Jan 2024)

Feeding spray-dried plasma to broilers early in life improved their intestinal development, immunity and performance irrespective of mycotoxins in feed

  • Gabriela Gómez-Verduzco,
  • José Arce-Menocal,
  • Carlos López-Coello,
  • Ernesto Avila-González,
  • Claudia C. Márquez-Mota,
  • Javier Polo,
  • Luis Rangel

DOI
https://doi.org/10.3389/fvets.2023.1321351
Journal volume & issue
Vol. 10

Abstract

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IntroductionFungi that produce mycotoxins can grow on certain food products, such as grains and feed, and can cause a variety of health issues if consumed by animals, including chickens. The use of spray-dried plasma (SDP) is one strategy for combating the health problems caused by mycotoxins.Materials and methodsIn the present study, Ross 308 chickens (n = 960) were divided into four treatment groups. T1 group was given a control diet (corn–soybean meal), T2 group was given a control diet +2% SDP, T3 group was given a control diet +2% SDP + mixture mycotoxins and T4 group was givena control diet + mycotoxin mixture.ResultsThe presence of SDP resulted in weight gain and decreased feed efficiency, whereas mycotoxins resulted in weight loss and increased feed efficiency. SDP increased the thymus’ relative weight. The presence of mycotoxins increased the heterophile/lymphocyte ratio. The presence of mycotoxins reduced the production of IL-2 and macrophage inflammatory protein-3 Alpha (MIP-3a), whereas the presence of SDP increased the production of macrophage colony-stimulating Factor (M-CSF). SDP resulted in higher IgA concentrations in the intestinal and tracheal washes than mycotoxin. Finally, adding SDP to broiler diets boosts weight gain, feed efficiency, and immune system development.DiscussionOur results provide information supporting that SDP is a promising tool for improving poultry immunity and performance.

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