Frontiers in Surgery (Mar 2022)

Current Opinion and Practice on Peritoneal Carcinomatosis Management: The North African Perspective

  • Amine Souadka,
  • Hajar Essangri,
  • Amin Makni,
  • Mourad Abid,
  • Mouna Ayadi,
  • Feriel Ksantini,
  • Zakia Kordjani,
  • Yousri Ballah,
  • Jemila Bouka,
  • Amine Benkabbou,
  • Mohammed Anass Majbar,
  • Basma El Khannoussi,
  • Raouf Mohsine,
  • Saber Boutayeb,
  • Martin Hubner

DOI
https://doi.org/10.3389/fsurg.2022.798523
Journal volume & issue
Vol. 9

Abstract

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BackgroundThe status of peritoneal surface malignancy (PSM) management in North Africa is undetermined. The aim of this study was to assess and compare current practice and knowledge regarding PSM and examine satisfaction with available treatment options and need for alternative therapies in North Africa.MethodsThis is a qualitative study involving specialists participating in PSM management in North Africa. The survey analyzed demographic characteristics and current knowledge and opinions regarding PSM management in different institutions. We also looked at goals and priorities, satisfaction with treatment modalities and heated intraperitoneal chemotherapy (HIPEC) usefulness according to specialty, country, years of experience, and activity sector.ResultsOne-hundred and three participants responded to the survey (response rate of 57%), including oncologists and surgeons. 59.2% of respondents had more than 10 years experience and 45.6% treated 20–50 PSM cases annually. Participants satisfaction with PSM treatment modalities was mild for gastric cancer (3/10 [IQR 2–3]) and moderate for colorectal (5/10 [IQR 3–5]), ovarian (5/10 [IQR 3–5]), and pseudomyxoma peritonei (5/10 [IQR 3–5]) type of malignancies. Good quality of life and symptom relief were rated as main priorities for treatment and the need for new treatment modalities was rated 9/10 [IQR 8–9]. The perceived usefulness of systemic chemotherapy in first intention was described as high by 42.7 and 39.8% of respondents for PSM of colorectal and gastric origins, while HIPEC was described as highly useful for ovarian (49.5%) and PMP (73.8) malignancies.ConclusionsThe management of PSM in the North African region has distinct differences in knowledge, treatments availability and priorities. Disparities are also noted according to specialty, country, years of expertise, and activity sector. The creation of referral structures and PSM networks could be a step forward to standardized PSM management in the region.

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