Combined Thrombophilia in a Young Male Presenting as Life Threatening Pulmonary Embolism

Abstract

Combined hereditary thrombophilia is an uncommon entity associated with higher risk of early onset thrombosis. We report a case of 39-year-old male with combined deficiency of natural anticoagulants (protein C, S and anti thrombin) along with hyper homocystenemia and factor V Leiden mutation, presenting with life threatening bilateral pulmonary embolism. The clinical implications of combined thrombophilia are also discussed.

Keywords

• anti thrombin
• fibrinolysis
• protein c
• protein s